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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1494783Generated: October 30, 2026

1-(4-Fluorophenyl)-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid → HCID 14795822, compound

https://huagongshe.com/reaction/1494783

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Fluorophenyl)-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acidHCID 13728330—
Reactant5-BromoisoindolineHCID 14795871—
SolventDimethylformamideHCID 6228—
ProductHCID 14795822HCID 1479582255.4%

Reaction Steps

170 mg of 1-(4-fluorophenyl)-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, 300 mg of 5- bromoisoindoline, and 1.5 ml of anhydrous DMF were processed in the same manner as in Example 20 to produce 144 mg of the target compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05026856
Source datasetuspto-grants-1991_06
ORD IDord-6fdca35d66034c5a8b755d6fba872197
Source noteuspto-grants-1991_06