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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1494786Generated: October 30, 2026

Isoindoline → HCID 14795827, compound

https://huagongshe.com/reaction/1494786

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsoindolineHCID 422478—
Reactant1-(2,4-Difluorophenyl)-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acidHCID 14476011—
SolventDimethylformamideHCID 6228—
ProductHCID 14795827HCID 1479582733.4%

Reaction Steps

178 mg of 1-(2,4-difluorophenyl)-6,7,8-trifluoro-1,4- dihydro-4-oxoquinoline-3-carboxylic acid, 179 mg of isoindoline, and 1.5 ml of anhydrous DMF were processed in the same manner as in Example 20 to produce 76 mg of the target compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05026856
Source datasetuspto-grants-1991_06
ORD IDord-02d0550a99d2431d9f0f0eca23ddd323
Source noteuspto-grants-1991_06