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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1494796Generated: October 30, 2026

1-(4-Fluorophenyl)-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid → HCID 14795837, compound

https://huagongshe.com/reaction/1494796

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Fluorophenyl)-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acidHCID 13728330—
Reactant5-ChloroisoindolineHCID 14795866—
SolventDimethylformamideHCID 6228—
ProductHCID 14795837HCID 1479583764.9%

Reaction Steps

170 mg of 1-(4-fluorophenyl)-6,7,8-trifluoro-1,4dihydro-4-oxoquinoline-3-carboxylic acid, 260 mg of 5-chloroisoindoline, and 1.5 ml of anhydrous DMF were processed in the same manner as in Example 20 to produce 154 mg of the target compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05026856
Source datasetuspto-grants-1991_06
ORD IDord-554dfc0a38e34681a9af96d487246939
Source noteuspto-grants-1991_06