HCID 53857087, compound → HCID 14795873, compound

Participants

Reaction Steps

150 mg of 7-(2-isoindolinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid ethyl ester was dissolved in a mixture of 10 ml of 10% hydrochloric acid and 10 ml of ethanol. The mixture was heated under reflux for 2 hours. The precipitates deposited were collected by filteration, and washed with water and ethanol in this order to obtain 107 mg of 7-(2- isoindolinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8- naphthyridine-3-carboxylic acid.

Provenance & Evidence