HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 14795880, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Ethyl 7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate | HCID 11722954 | — |
| Reactant | 4-methoxy-2,3-dihydro-1H-isoindole | HCID 14795864 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 14795880 | HCID 14795880 | 29.9% |
Reaction Steps
310 mg of 1-cyclopropyl-6-fluoro-7-chloro-1,4-dihydro-4- oxo-1,8-naphthyridine-3-carboxylic acid ethyl ester, 298 mg of 4-methoxyisoindoline, 0.42 ml of triethylamine, and 5 ml of anhydrous chloroform were processed in the same manner as in Example 107 to produce 118 mg of 7-(4-methoxy-2- isoindolinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8- naphthyridine-3-carboxylic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05026856 |
| Source dataset | uspto-grants-1991_06 |
| ORD ID | ord-db20d75dac4a48b19c4d922deb0acf26 |
| Source note | uspto-grants-1991_06 |