Potassium Cation → Tert-butyl 4-(6-chloropyrazin-2-YL)piperazine-1-carboxylate

HRID 149562Notes

Reaction equation

HRID 149562 reaction equation
[CH3:28][C:29]#[N:30].[Cl:14][c:15]1[n:16][c:17]([Cl:21])[cH:18][n:19][cH:20]1.[K+:22].[K+:23].[N:1]1([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:2][CH2:3][NH:4][CH2:5][CH2:6]1.[O-:24][C:25]([O-:26])=[O:27]>>[N:1]1([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:2][CH2:3][N:4]([c:17]2[n:16][c:15]([Cl:14])[cH:20][n:19][cH:18]2)[CH2:5][CH2:6]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6342AcetonitrileHCID 19660Carbonate IonHCID 785042,6-DichloropyrazineHCID 143452tert-Butyl piperazine-1-carboxylate

Product 1

HCID 18186946Tert-butyl 4-(6-chloropyrazin-2-YL)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-824d861701cf4ae18533225bbb3a1248
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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