3-(Trifluoromethyl)anisole → 4-Methyl-3'-trifluoromethylbiphenyl
Reaction equation
COc1cccc(C(F)(F)F)c1.Cc1ccc([Mg]Br)cc1>>Cc1ccc(-c2cccc(C(F)(F)F)c2)cc1Participants
3
Conditions
- Temperature
- 60 °C
Sources & evidence
- ORD record
- ord-a08181e7e9d14faabb2af9a10cf4bb37
- Source dataset
- NiCOlit
Reaction notes
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