Water → HCID 118062880, compound

Participants

Reaction Steps

The reaction afforded the desired quaternized salt in 88% yield (37 g) as off-white shinny powder. The obtained 1,1,2-trimethyloctahydroindolium iodide was dissolved in 130 ml of deionized water in 250 ml polyethylene plastic bottle. To the solution, 41 g of Bio-Rad AG 1-X8 ion exchange resins was added and the slurry was gently stirred at room temperature overnight. The slurry was then filtered and the resin was rinsed with additional 50 ml water (deionized). A small aliquot of the water layer was analyzed by titration with 0.1 N HCl to show 96% yield of the desired 1,1,2-trimethyloctahydroindolium hydroxide in solution.

Provenance & Evidence