3,4-Dichlorophenol → HCID 68588944, compound

Participants

Reaction Conditions

Reaction Steps

10.0 g (61.3 mmol) of 3,4-dichlorophenol, 10.4 g (55.8 mmol) of 4-chloro-2,5-dimethylnitrobenzene and 10.0 g (72.5 mmol) of potassium carbonate are stirred in 200 ml of N,N-dimethylformamide at 100° C. for 6 h, and the mixture is applied to ice, stirred at 0° C. for 15 min and then filtered. The solid is washed with water and hexane and dried under reduced pressure (18.0 g, 98.3% purity, 98.0% yield, log P (pH 2.3)=5.19).

Provenance & Evidence