Dipropylamine → HCID 68593802, compound

HRID 1496836Notes

Reaction equation

HRID 1496836 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([CH:17]=[CH:18][C:19]=1[CH3:20])[C:5]([C:7]1([OH:16])[CH2:12][CH2:11][CH2:10][CH2:9][CH:8]1[C:13]([OH:15])=[O:14])=[O:6].[CH2:21]([NH:24][CH2:25][CH2:26][CH3:27])[CH2:22][CH3:23]>CC(C)=O>[CH2:21]([NH2+:24][CH2:25][CH2:26][CH3:27])[CH2:22][CH3:23].[CH3:1][C:2]1[CH:3]=[C:4]([CH:17]=[CH:18][C:19]=1[CH3:20])[C:5]([C:7]1([OH:16])[CH2:12][CH2:11][CH2:10][CH2:9][CH:8]1[C:13]([O-:15])=[O:14])=[O:6]

Participants

4

Reactant 2

HCID 8902DipropylamineHCID 59289832HCID 59289832, compound

Product 1

HCID 68593802HCID 68593802, compoundYield 98%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent2×

Procedure

5.53 g (0.02 mol) of 2-(3,4-dimethyl-benzoyl)-2-hydroxy-cyclohexanecarboxylic acid (=compound of example 3) are dissolved in 30 ml of acetone. A solution of 2.02 g (0.02 mol) of dipropylamine in 30 ml of acetone and the reaction mixture are stirred at room temperature for 30 minutes. The solvent is evaporated in vacuum and the remaining residue is dried in vacuum. 7.4 g of 2-(3,4-dimethyl-benzoyl)-2-hydroxy-cyclohexanecarboxylate dipropyl-ammonium are obtained as slightly yellowish crystals with a melting range of 122-129° C.

Workup

  1. customThe solvent is evaporated in vacuum
  2. customthe remaining residue is dried in vacuum

Sources & evidence

ORD record
ord-0b2002febf0b48ab9efd772383d751ac
Source dataset
uspto-grants-2015_12
Patent number
US09199934B2

Reaction notes

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