Benzoyl isocyanate → HCID 58602980, compound

Participants

Reaction Steps

To a solution of benzoylisocyanate (4.8 g, 32.6 mmol) in CH2Cl2 (180 mL) at 0° C. was added 4-amino-1-N-boc-piperidine (6.0 g, 30 mmol). The reaction mixture was stirred at room temperature for 4 h and concentrated. The residue was treated with Et2O (100 mL). The precipitate was filtered, washed with Et2O to yield a white solid (5.70 g, yield 55%). LC/MS: m/z (ES+) 337 (M+H)+.

Provenance & Evidence