1-(4-(3-Ethoxy-4-nitrophenyl)piperazin-1-yl)ethanone → 1-(4-(4-Amino-3-ethoxyphenyl)piperazin-1-yl)ethanone

Participants

Reaction Steps

The compound prepared in Step 2 was dissolved in ethanol, added with 10% Pd/C and stirred under hydrogen atmosphere for 2 hours. Upon completion of the reaction, the Pd/C in the reaction mixture was removed using celite and the solvent was removed under reduced pressure. The thus obtained compound was used in the subsequent reaction without further purification.

Provenance & Evidence