HCID 118105736, compound → HCID 59291191, compound

HRID 1496952Notes

Reaction equation

HRID 1496952 reaction equation
[CH:1]([O:4][C:5]1[CH:6]=[C:7]([N:14]2[CH2:19][CH2:18][N:17]([C:20](=[O:22])[CH3:21])[CH2:16][CH2:15]2)[CH:8]=[CH:9][C:10]=1[N+:11]([O-])=O)([CH3:3])[CH3:2]>C(O)C.[Pd]>[NH2:11][C:10]1[CH:9]=[CH:8][C:7]([N:14]2[CH2:19][CH2:18][N:17]([C:20](=[O:22])[CH3:21])[CH2:16][CH2:15]2)=[CH:6][C:5]=1[O:4][CH:1]([CH3:3])[CH3:2]

Participants

4

Reactant 1

HCID 118105736HCID 118105736, compound

Product 1

HCID 59291191HCID 59291191, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

The compound prepared in Step 2 was dissolved in ethanol, added with 10% Pd/C and stirred under hydrogen atmosphere for 2 hours. Upon completion of the reaction, the Pd/C in the reaction mixture was removed using celite and the solvent was removed under reduced pressure. The thus obtained compound was used in the subsequent reaction without further purification.

Workup

  1. customUpon completion of the reaction
  2. customthe Pd/C in the reaction mixture was removed
  3. customthe solvent was removed under reduced pressure
  4. customThe thus obtained compound was used in the subsequent reaction without further purification

Sources & evidence

ORD record
ord-57bbd3b8f81a4b9bad7cc4755ee41dc8
Source dataset
uspto-grants-2015_12
Patent number
US09199944B2

Reaction notes

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