HCID 118105716, compound → HCID 118105655, compound

HRID 1496955Notes

Reaction equation

HRID 1496955 reaction equation
[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([N:18]2[CH2:23][CH2:22][N:21]([C:24](=[O:26])[CH3:25])[CH2:20][CH2:19]2)[CH:12]=[CH:13][C:14]=1[N+:15]([O-])=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C(O)C.[Pd]>[NH2:15][C:14]1[CH:13]=[CH:12][C:11]([N:18]2[CH2:23][CH2:22][N:21]([C:24](=[O:26])[CH3:25])[CH2:20][CH2:19]2)=[CH:10][C:9]=1[O:8][CH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 1

HCID 118105716HCID 118105716, compound

Product 1

HCID 118105655HCID 118105655, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

The compound prepared in Step 2 was dissolved in ethanol, added with 10% Pd/C and stirred under hydrogen atmosphere for 2 hours. Upon completion of the reaction, the Pd/C in the reaction mixture was removed using celite and the solvent was removed under reduced pressure. The thus obtained compound was used in the subsequent reaction without further purification.

Workup

  1. customUpon completion of the reaction
  2. customthe Pd/C in the reaction mixture was removed
  3. customthe solvent was removed under reduced pressure
  4. customThe thus obtained compound was used in the subsequent reaction without further purification

Sources & evidence

ORD record
ord-4b9204cf10fc400a937ab88a52197683
Source dataset
uspto-grants-2015_12
Patent number
US09199944B2

Reaction notes

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