HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 6-Chloro-4-phenyl-2-(2,2,2-trifluoro-ethoxy)-quinoline-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 86682930 | HCID 86682930 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 6-Chloro-4-phenyl-2-(2,2,2-trifluoro-ethoxy)-quinoline-3-carboxylic acid | HCID 71556229 | — |
Reaction Steps
The title compound was prepared in analogy to example 6 step B from a mixture of 6-chloro-4-phenyl-2-(2,2,2-trifluoro-ethoxy)-quinoline-3-carboxylic acid ethyl ester and 1N NaOH in ethanol. Off white solid (19.2 mg, 17%). LC-MS: 382 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09199938B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-5dc338a422c84810b1c36c14b66709c2 |
| Source note | uspto-grants-2015_12 |