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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1497061Generated: October 25, 2026

Isopropanol → 6-Chloro-2-isopropoxy-4-phenyl-quinoline-3-carboxylic acid ethyl ester

https://huagongshe.com/reaction/1497061

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsopropanolHCID 3776—
ReactantEthyl 2,6-dichloro-4-phenylquinoline-3-carboxylateHCID 1714247—
Product6-Chloro-2-isopropoxy-4-phenyl-quinoline-3-carboxylic acid ethyl esterHCID 86682933—

Reaction Steps

The title compound was prepared in analogy to example 11 step C from 2,6-dichloro-4-phenyl-quinoline-3-carboxylic acid ethyl ester (prepared as described in example 11 step B) and propan-2-ol. Yellow solid (35 mg, 33%). LC-MS: 370 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09199938B2
Source datasetuspto-grants-2015_12
ORD IDord-c387f456ae494703b722d7193b39508b
Source noteuspto-grants-2015_12