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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1497062Generated: October 31, 2026

Sodium Hydroxide → 6-Chloro-2-isopropoxy-4-phenyl-quinoline-3-carboxylic acid

https://huagongshe.com/reaction/1497062

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactant6-Chloro-2-isopropoxy-4-phenyl-quinoline-3-carboxylic acid ethyl esterHCID 86682933—
SolventEthanolHCID 702—
Product6-Chloro-2-isopropoxy-4-phenyl-quinoline-3-carboxylic acidHCID 71556291—

Reaction Steps

The title compound was prepared in analogy to example 6 step B from a mixture of 6-chloro-2-isopropoxy-4-phenyl-quinoline-3-carboxylic acid ethyl ester and 1N NaOH in ethanol. Off white solid (17.2 mg, 47%). LC-MS: 342 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09199938B2
Source datasetuspto-grants-2015_12
ORD IDord-4b0c1a69d92d43afb9ab2316d2a0591a
Source noteuspto-grants-2015_12