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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1497064Generated: November 1, 2026

Sodium Hydroxide → 6-Chloro-2-cyclopentyloxy-4-phenyl-quinoline-3-carboxylic acid

https://huagongshe.com/reaction/1497064

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactant6-Chloro-2-cyclopentyloxy-4-phenyl-quinoline-3-carboxylic acid ethyl esterHCID 86682934—
SolventEthanolHCID 702—
Product6-Chloro-2-cyclopentyloxy-4-phenyl-quinoline-3-carboxylic acidHCID 71556293—

Reaction Steps

The title compound was prepared in analogy to example 6 step B from a mixture of 6-chloro-2-cyclopentyloxy-4-phenyl-quinoline-3-carboxylic acid ethyl ester and 1N NaOH in ethanol. Off white solid (28.5 mg, 77%). LC-MS: 368 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09199938B2
Source datasetuspto-grants-2015_12
ORD IDord-76b14e9e40894842945ff7313385ec8b
Source noteuspto-grants-2015_12