3-Cyclopropyl-3-Oxopropionic Acid Methyl Ester → HCID 86682936, compound

HRID 1497067Notes

Reaction equation

HRID 1497067 reaction equation
[NH2:1][C:2]1[CH:7]=[C:6]([Cl:8])[C:5]([Cl:9])=[CH:4][C:3]=1[C:10]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=O.[CH:18]1([C:21](=O)[CH2:22][C:23]([O:25][CH3:26])=[O:24])[CH2:20][CH2:19]1>>[CH3:26][O:25][C:23]([C:22]1[C:21]([CH:18]2[CH2:20][CH2:19]2)=[N:1][C:2]2[C:3]([C:10]=1[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=[CH:4][C:5]([Cl:9])=[C:6]([Cl:8])[CH:7]=2)=[O:24]

Participants

3

Reactant 2

HCID 101300163-Cyclopropyl-3-Oxopropionic Acid Methyl EsterHCID 12382440HCID 12382440, compound

Product 1

HCID 86682936HCID 86682936, compound

Procedure

The title compound was prepared in analogy to example 6 step A from a mixture of (2-amino-4,5-dichloro-phenyl)-phenyl-methanone and methyl 3-cyclopropyl-3-oxopropanoate. Yellow solid. MS (ESI): 372.1 (M+H)+.

Sources & evidence

ORD record
ord-c3246f1439034374ab764354c5a59d27
Source dataset
uspto-grants-2015_12
Patent number
US09199938B2

Reaction notes

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