Potassium Hydroxide → HCID 71556295, compound

HRID 1497068Notes

Reaction equation

HRID 1497068 reaction equation
C[O:2][C:3]([C:5]1[C:6]([CH:23]2[CH2:25][CH2:24]2)=[N:7][C:8]2[C:13]([C:14]=1[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)=[CH:12][C:11]([Cl:21])=[C:10]([Cl:22])[CH:9]=2)=[O:4].[OH-].[K+]>C(O)C.O>[Cl:21][C:11]1[CH:12]=[C:13]2[C:8](=[CH:9][C:10]=1[Cl:22])[N:7]=[C:6]([CH:23]1[CH2:24][CH2:25]1)[C:5]([C:3]([OH:4])=[O:2])=[C:14]2[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 86682936HCID 86682936, compound

Product 1

HCID 71556295HCID 71556295, compound

Reagents, catalysts & solvents 1

HCID 19096565Water ethanolSolvent

Procedure

The title compound was prepared in analogy to example 6 step B from a mixture of 6,7-dichloro-2-cyclopropyl-4-phenyl-quinoline-3-carboxylic acid methyl ester and KOH in a mixture of ethanol/water. White solid. MS (ESI): 358.0 (M+H)+.

Sources & evidence

ORD record
ord-8c1d18f695584e0d91773d64bc668613
Source dataset
uspto-grants-2015_12
Patent number
US09199938B2

Reaction notes

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