Methyl malonyl chloride → HCID 86682968, compound

HRID 1497116Notes

Reaction equation

HRID 1497116 reaction equation
[NH2:1][C:2]1[C:7]([CH2:8][CH3:9])=[CH:6][CH:5]=[CH:4][C:3]=1[C:10]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=[O:11].Cl[C:19](=[O:25])[CH2:20][C:21]([O:23][CH3:24])=[O:22]>>[CH3:24][O:23][C:21](=[O:22])[CH2:20][C:19]([NH:1][C:2]1[C:7]([CH2:8][CH3:9])=[CH:6][CH:5]=[CH:4][C:3]=1[C:10](=[O:11])[C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1)=[O:25]

Participants

3

Reactant 2

HCID 123460Methyl malonyl chlorideHCID 15634761HCID 15634761, compound

Product 1

HCID 86682968HCID 86682968, compound

Procedure

The title compound was prepared in analogy to example 21 step A from (2-amino-3-ethyl-phenyl)-phenyl-methanone and methyl 3-chloro-3-oxopropanoate. White solid. MS (ESI): 326.2 (M+H)+.

Sources & evidence

ORD record
ord-870d746c052b47bfafd20fb970a489d3
Source dataset
uspto-grants-2015_12
Patent number
US09199938B2

Reaction notes

Loading…