Dimethylamine → HCID 71556617, compound

HRID 1497122Notes

Reaction equation

C[O:2][C:3]([C:5]1[C:6](Cl)=[N:7][C:8]2[C:13]([C:14]=1[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)=[CH:12][CH:11]=[CH:10][C:9]=2[CH2:21][CH3:22])=[O:4].[CH3:24][NH:25][CH3:26]>>[CH3:24][N:25]([CH3:26])[C:6]1[C:5]([C:3]([OH:2])=[O:4])=[C:14]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[C:13]2[C:8](=[C:9]([CH2:21][CH3:22])[CH:10]=[CH:11][CH:12]=2)[N:7]=1

Participants

Reactant 2

HCID 674Dimethylamine

HCID 86682970HCID 86682970, compound

Product 1

HCID 71556617HCID 71556617, compound

Procedure

The title compound was prepared in analogy to example 43 step E from 2-chloro-8-ethyl-4-phenyl-quinoline-3-carboxylic acid methyl ester (prepared as described in example 43 step D) and dimethylamine (40% in water). Yellow solid. MS (ESI): 321.2 (M+H)+.

Sources & evidence

ORD record: ord-cf8274edb07f499f96805435551cf692
Source dataset: uspto-grants-2015_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09199938B2

Reaction notes

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