N-Methylisopropylamine → HCID 86682989, compound

HRID 1497150Notes

Reaction equation

HRID 1497150 reaction equation
Cl[C:2]1[C:11]([C:12]#[N:13])=[C:10]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:20])[CH:8]=2)[N:3]=1.[CH:21]([NH:24][CH3:25])([CH3:23])[CH3:22]>>[Cl:20][C:7]1[CH:8]=[C:9]2[C:4](=[CH:5][CH:6]=1)[N:3]=[C:2]([N:24]([CH:21]([CH3:23])[CH3:22])[CH3:25])[C:11]([C:12]#[N:13])=[C:10]2[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

Participants

3

Reactant 2

HCID 78485N-MethylisopropylamineHCID 86682946HCID 86682946, compound

Product 1

HCID 86682989HCID 86682989, compound

Procedure

The title compound was prepared in analogy to example 27 step C from 2,6-dichloro-4-phenyl-quinoline-3-carbonitrile (prepared as described in example 27 step B) and isopropyl-methyl-amine. Yellow solid. MS (ESI): 336.2 (M+H)+.

Sources & evidence

ORD record
ord-477555b3844c44c9bd628ccdd575db0b
Source dataset
uspto-grants-2015_12
Patent number
US09199938B2

Reaction notes

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