3-Isopropylbenzeneboronic acid → HCID 86682999, compound

HRID 1497160Notes

Reaction equation

HRID 1497160 reaction equation
[CH3:1][O:2][C:3]([C:5]1[C:6]([CH:25]([CH3:27])[CH3:26])=[N:7][C:8]2[C:13]([C:14]=1OS(C(F)(F)F)(=O)=O)=[CH:12][C:11]([Cl:23])=[CH:10][C:9]=2[Cl:24])=[O:4].[CH:28]([C:31]1[CH:32]=[C:33](B(O)O)[CH:34]=[CH:35][CH:36]=1)([CH3:30])[CH3:29]>>[CH3:1][O:2][C:3]([C:5]1[C:6]([CH:25]([CH3:27])[CH3:26])=[N:7][C:8]2[C:13]([C:14]=1[C:35]1[CH:34]=[CH:33][CH:32]=[C:31]([CH:28]([CH3:30])[CH3:29])[CH:36]=1)=[CH:12][C:11]([Cl:23])=[CH:10][C:9]=2[Cl:24])=[O:4]

Participants

3

Reactant 2

HCID 27734783-Isopropylbenzeneboronic acidHCID 86682995HCID 86682995, compound

Product 1

HCID 86682999HCID 86682999, compound

Procedure

The title compound was prepared in analogy to example 72 step C from 6,8-dichloro-2-isopropyl-4-trifluoromethanesulfonyloxy-quinoline-3-carboxylic acid methyl ester (prepared as described in example 72 step B) and 3-isopropylphenylboronic acid. Colorless semisolid. MS (ESI): 416.1 (M+H)+.

Sources & evidence

ORD record
ord-5355afdb82dd4f65bcffe30deed4f76c
Source dataset
uspto-grants-2015_12
Patent number
US09199938B2

Reaction notes

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