HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-2-ethynylbenzene → HCID 86683001, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-2-ethynylbenzene | HCID 585995 | — |
| Reactant | 4-Chloro-2-iodo-6-methylaniline | HCID 15422784 | — |
| Product | HCID 86683001 | HCID 86683001 | 68.4% |
Reaction Steps
The title compound was prepared in analogy to example 10 step A from 4-chloro-2-iodo-6-methyl-phenylamine (1.5 g, 5.61 mmol) and 1-chloro-2-ethynyl-benzene (920 mg, 6.73 mmol) to afford 4-chloro-2-(2-chloro-phenylethynyl)-6-methyl-phenylamine (1.06 g, 68%) as an off white solid. LC-MS (ESI): 276 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09199938B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-df74a0c9e7aa4ff3a995ba07f6bfaedd |
| Source note | uspto-grants-2015_12 |