HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 71556886, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 86683010 | HCID 86683010 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 71556886 | HCID 71556886 | — |
Reaction Steps
The title compound was prepared in analogy to example 78 step E from 6-chloro-4-(3-isopropyl-phenyl)-2-piperidin-1-yl-quinoline-3-carboxylic acid tert-butyl ester (75 mg, 0.16 mmol) and 4N HCl in dioxane. Pale yellow solid (58 mg, 88%). LC-MS (ESI): 409 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09199938B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-f36ad21bd6aa4f8896a49c1c13cf48f4 |
| Source note | uspto-grants-2015_12 |