HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 71555919, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 86683012 | HCID 86683012 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 71555919 | HCID 71555919 | — |
Reaction Steps
The title compound was prepared in analogy to example 78 step E from 6-chloro-4-(3-isopropyl-phenyl)-2-(2,2,2-trifluoro-1-methyl-ethoxy)-quinoline-3-carboxylic acid tert-butyl ester (70 mg, 0.14 mmol) and 4N HCl in dioxane. Off white solid (44 mg, 71%). LC-MS (ESI): 438 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09199938B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-d47464d581cd47bb8bc114dde82429cf |
| Source note | uspto-grants-2015_12 |