HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-2-ethynylbenzene → 4-Chloro-2-(2-chloro-phenylethynyl)-6-trifluoromethyl-phenylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-2-ethynylbenzene | HCID 585995 | — |
| Reactant | 4-Chloro-2-iodo-6-(trifluoromethyl)aniline | HCID 66865667 | — |
| Product | 4-Chloro-2-(2-chloro-phenylethynyl)-6-trifluoromethyl-phenylamine | HCID 86683015 | — |
Reaction Steps
The title compound was prepared in analogy to example 10 step A from 4-chloro-2-iodo-6-trifluoromethyl-phenylamine (1.5 g, 4.67 mmol) and 1-chloro-2-ethynyl-benzene (766 mg, 5.6 mmol). Brown solid (1.05 g, 68%). LC-MS (ESI): 328 (M−H)−.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09199938B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-c46e245ab70e42149d131a6e04a884c2 |
| Source note | uspto-grants-2015_12 |