HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-chloro-3-oxopropionate → N-[4-Chloro-2-(2-chloro-phenylethynyl)-6-trifluoromethyl-phenyl]-malonamic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-chloro-3-oxopropionate | HCID 118931 | — |
| Reactant | 4-Chloro-2-(2-chloro-phenylethynyl)-6-trifluoromethyl-phenylamine | HCID 86683015 | — |
| Product | N-[4-Chloro-2-(2-chloro-phenylethynyl)-6-trifluoromethyl-phenyl]-malonamic acid ethyl ester | HCID 86683016 | — |
Reaction Steps
The title compound was prepared in analogy to example 29 step A from 4-chloro-2-(2-chloro-phenylethynyl)-6-trifluoromethyl-phenylamine and chlorocarbonyl-acetic acid ethyl ester. Off white solid (1.2 g, 45%) LC-MS (ESI): 444 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09199938B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-3bf7771b0c03486ab1be8987efe44df2 |
| Source note | uspto-grants-2015_12 |