HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → 4-Chloro-2-((2-(trifluoromethyl)phenyl)ethynyl)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | 4-Chloro-2-iodoaniline | HCID 2757615 | — |
| Reactant | 1-Ethynyl-2-(trifluoromethyl)benzene | HCID 4100856 | — |
| Solvent | Heptane | HCID 8900 | — |
| Product | 4-Chloro-2-((2-(trifluoromethyl)phenyl)ethynyl)aniline | HCID 86683023 | — |
Reaction Steps
The title compound was prepared in analogy to example 10 step A from 4-chloro-2-iodoaniline (500 mg, 1.97 mmol) and 1-ethynyl-2-(trifluoromethyl)benzene (330 μl, 2.37 mmol). Off white solid. Rf 0.3 (1:9 Ethyl acetate:heptane) as an intense blue spot under UV light.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09199938B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-bd9d89dda50f420ea6dbd71c2b1da6a2 |
| Source note | uspto-grants-2015_12 |