HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 71556051, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 86683041 | HCID 86683041 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 71556051 | HCID 71556051 | — |
Reaction Steps
The title compound was prepared in analogy to example 91 step E from 6-chloro-4-(3-chloro-phenyl)-2-(2,2,2-trifluoro-1-methyl-ethoxy)-quinoline-3-carboxylic acid tert-butyl ester (60 mg, 0.12 mmol) and 4N HCl in dioxane. Off white solid (21 mg, 40%). LC-MS (ESI): 428 (M−H)−.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09199938B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-e73558f1687645f28da247f14e447920 |
| Source note | uspto-grants-2015_12 |