N-Methylethylamine → HCID 86683047, compound

HRID 1497226Notes

Reaction equation

HRID 1497226 reaction equation
Cl[C:2]1[C:11]([C:12]#[N:13])=[C:10]([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([CH:20]([CH3:22])[CH3:21])[CH:15]=2)[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:23])[CH:8]=2)[N:3]=1.[CH2:24]([NH:26][CH3:27])[CH3:25]>>[Cl:23][C:7]1[CH:8]=[C:9]2[C:4](=[CH:5][CH:6]=1)[N:3]=[C:2]([N:26]([CH2:24][CH3:25])[CH3:27])[C:11]([C:12]#[N:13])=[C:10]2[C:14]1[CH:19]=[CH:18][CH:17]=[C:16]([CH:20]([CH3:22])[CH3:21])[CH:15]=1

Participants

3

Reactant 2

HCID 12219N-MethylethylamineHCID 86683045HCID 86683045, compound

Product 1

HCID 86683047HCID 86683047, compound

Procedure

The title compound was prepared in analogy to example 98 step E from 2,6-dichloro-4-(3-isopropyl-phenyl)-quinoline-3-carbonitrile (prepared as described in example 98 step D) and ethyl-methyl-amine. Light yellow oil. MS (ESI): 364.2 (M+H)+.

Sources & evidence

ORD record
ord-893f3ce3186a4849a5b00f24e077be8f
Source dataset
uspto-grants-2015_12
Patent number
US09199938B2

Reaction notes

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