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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1497244Generated: October 31, 2026

3-Cyclopentyl-3-oxopropanenitrile → 6-Chloro-2-cyclopentyl-7-fluoro-4-phenyl-quinoline-3-carbonitrile

https://huagongshe.com/reaction/1497244

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Cyclopentyl-3-oxopropanenitrileHCID 13592118—
Reactant(2-Amino-5-chloro-4-fluoro-phenyl)-phenyl-methanoneHCID 86683059—
Product6-Chloro-2-cyclopentyl-7-fluoro-4-phenyl-quinoline-3-carbonitrileHCID 86683060—

Reaction Steps

The title compound was prepared in analogy to example 101 step B from (2-amino-5-chloro-4-fluoro-phenyl)-phenyl-methanone and 3-cyclopentyl-3-oxo-propionitrile. Off-white solid. MS (ESI): 351.4 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09199938B2
Source datasetuspto-grants-2015_12
ORD IDord-fd977fb7b8694286a0ed62d227dd0dd1
Source noteuspto-grants-2015_12