HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Ethyl-3-oxohexanenitrile → 6-Chloro-2-(1-ethyl-propyl)-7-fluoro-4-phenyl-quinoline-3-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Ethyl-3-oxohexanenitrile | HCID 23505748 | — |
| Reactant | (2-Amino-5-chloro-4-fluoro-phenyl)-phenyl-methanone | HCID 86683059 | — |
| Product | 6-Chloro-2-(1-ethyl-propyl)-7-fluoro-4-phenyl-quinoline-3-carbonitrile | HCID 86683061 | — |
Reaction Steps
The title compound was prepared in analogy to example 101 step B from (2-amino-5-chloro-4-fluoro-phenyl)-phenyl-methanone (prepared as described in example 105 step D) and 4-ethyl-3-oxo-hexanenitrile (prepared as described in example 101 step A). Off-white solid. MS (ESI): 353.4 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09199938B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-65cca63271c84d678dabe1171288a391 |
| Source note | uspto-grants-2015_12 |