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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1497249Generated: October 30, 2026

(2-Amino-5-chlorophenyl)(3-chlorophenyl)methanone → 6-Chloro-4-(3-chloro-phenyl)-2-(1-ethyl-propyl)-quinoline-3-carbonitrile

https://huagongshe.com/reaction/1497249

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Amino-5-chlorophenyl)(3-chlorophenyl)methanoneHCID 5231029—
Reactant4-Ethyl-3-oxohexanenitrileHCID 23505748—
Product6-Chloro-4-(3-chloro-phenyl)-2-(1-ethyl-propyl)-quinoline-3-carbonitrileHCID 86683066—

Reaction Steps

The title compound was prepared in analogy to example 101 step B from (2-amino-5-chloro-phenyl)-(3-chloro-phenyl)-methanone (prepared as described in example 91 step A) and 4-ethyl-3-oxo-hexanenitrile (prepared as described in example 101 step A). Light yellow oil. MS (ESI): 369.3 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09199938B2
Source datasetuspto-grants-2015_12
ORD IDord-4cb5d45c2e654bee805c9bdde524a8d5
Source noteuspto-grants-2015_12