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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1497254Generated: November 1, 2026

(2-Amino-5-(trifluoromethyl)phenyl)(phenyl)methanone → 2-Cyclopentyl-4-phenyl-6-trifluoromethyl-quinoline-3-carbonitrile

https://huagongshe.com/reaction/1497254

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Amino-5-(trifluoromethyl)phenyl)(phenyl)methanoneHCID 13014169—
Reactant3-Cyclopentyl-3-oxopropanenitrileHCID 13592118—
Product2-Cyclopentyl-4-phenyl-6-trifluoromethyl-quinoline-3-carbonitrileHCID 86683070—

Reaction Steps

The title compound was prepared in analogy to example 101 step B from (2-amino-5-trifluoromethyl-phenyl)-phenyl-methanone and 3-cyclopentyl-3-oxo-propionitrile (prepared as described in example 105 step A). White solid. MS (ESI): 367.4 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09199938B2
Source datasetuspto-grants-2015_12
ORD IDord-d477281f28db43cc8a95d9c44b79fd18
Source noteuspto-grants-2015_12