HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Cyclohexyl-3-oxopropanenitrile → 6-Chloro-2-cyclohexyl-7-fluoro-4-phenyl-quinoline-3-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Cyclohexyl-3-oxopropanenitrile | HCID 11309597 | — |
| Reactant | (2-Amino-5-chloro-4-fluoro-phenyl)-phenyl-methanone | HCID 86683059 | — |
| Product | 6-Chloro-2-cyclohexyl-7-fluoro-4-phenyl-quinoline-3-carbonitrile | HCID 86683071 | — |
Reaction Steps
The title compound was prepared in analogy to example 101 step B from (2-amino-5-chloro-4-fluoro-phenyl)-phenyl-methanone (prepared as described in example 105 step D) and 3-cyclohexyl-3-oxo-propionitrile (prepared as described in example 110 step A). Off-white solid. MS (ESI): 365.4 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09199938B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-90f8e2460f7348ae9735ffc647bb787b |
| Source note | uspto-grants-2015_12 |