3-Cyclohexyl-3-oxopropanenitrile → HCID 86683072, compound

HRID 1497256Notes

Reaction equation

HRID 1497256 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([F:11])([F:10])[F:9])=[CH:4][C:3]=1[C:12]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)=O.[CH:20]1([C:26](=O)[CH2:27][C:28]#[N:29])[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]1>>[CH:20]1([C:26]2[C:27]([C:28]#[N:29])=[C:12]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[C:3]3[C:2](=[CH:7][CH:6]=[C:5]([C:8]([F:11])([F:10])[F:9])[CH:4]=3)[N:1]=2)[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]1

Participants

3

Reactant 2

HCID 113095973-Cyclohexyl-3-oxopropanenitrileHCID 13014169(2-Amino-5-(trifluoromethyl)phenyl)(phenyl)methanone

Product 1

HCID 86683072HCID 86683072, compound

Procedure

The title compound was prepared in analogy to example 101 step B from (2-amino-5-trifluoromethyl-phenyl)-phenyl-methanone and 3-cyclohexyl-3-oxo-propionitrile (prepared as described in example 110 step A). Off-white solid. MS (ESI): 381.4 (M+H)+.

Sources & evidence

ORD record
ord-c67a36ea46704f6d92d9896283bef620
Source dataset
uspto-grants-2015_12
Patent number
US09199938B2

Reaction notes

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