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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1497257Generated: November 1, 2026

(2-Amino-5-chlorophenyl)(3-chlorophenyl)methanone → 6-Chloro-4-(3-chloro-phenyl)-2-isopropyl-quinoline-3-carbonitrile

https://huagongshe.com/reaction/1497257

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Amino-5-chlorophenyl)(3-chlorophenyl)methanoneHCID 5231029—
Reactant4-Methyl-3-oxopentanenitrileHCID 10129921—
Product6-Chloro-4-(3-chloro-phenyl)-2-isopropyl-quinoline-3-carbonitrileHCID 86683073—

Reaction Steps

The title compound was prepared in analogy to example 101 step B from (2-amino-5-chloro-phenyl)-(3-chloro-phenyl)-methanone (prepared as described in example 91 step A) and 4-methyl-3-oxo-pentanenitrile. Light yellow solid. MS (ESI): 341.3 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09199938B2
Source datasetuspto-grants-2015_12
ORD IDord-f05cedb8ac3a436685a32b3f73ded915
Source noteuspto-grants-2015_12