Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1497258Generated: October 31, 2026

(2-Amino-5-chlorophenyl)(3-chlorophenyl)methanone → 6-Chloro-4-(3-chloro-phenyl)-2-cyclopropyl-quinoline-3-carbonitrile

https://huagongshe.com/reaction/1497258

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Amino-5-chlorophenyl)(3-chlorophenyl)methanoneHCID 5231029—
Reactant3-Cyclopropyl-3-oxopropanenitrileHCID 9812763—
Product6-Chloro-4-(3-chloro-phenyl)-2-cyclopropyl-quinoline-3-carbonitrileHCID 86683074—

Reaction Steps

The title compound was prepared in analogy to example 101 step B from (2-amino-5-chloro-phenyl)-(3-chloro-phenyl)-methanone (prepared as described in example 91 step A) and 3-cyclopropyl-3-oxo-propionitrile. Light yellow solid. MS (ESI): 339.3 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09199938B2
Source datasetuspto-grants-2015_12
ORD IDord-64a787dd445d4c4fbd795210f7ab124b
Source noteuspto-grants-2015_12