(2-Amino-4-methoxyphenyl)(phenyl)methanone → HCID 86683078, compound
Reaction equation
[NH2:1][C:2]1[CH:7]=[C:6]([O:8][CH3:9])[CH:5]=[CH:4][C:3]=1[C:10]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=O.[CH2:18]([CH:20]([CH2:26][CH3:27])[C:21](=O)[CH2:22][C:23]#[N:24])[CH3:19]>>[CH2:18]([CH:20]([C:21]1[C:22]([C:23]#[N:24])=[C:10]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[C:3]2[C:2](=[CH:7][C:6]([O:8][CH3:9])=[CH:5][CH:4]=2)[N:1]=1)[CH2:26][CH3:27])[CH3:19]Participants
3
Procedure
The title compound was prepared in analogy to example 101 step B from (2-amino-4-methoxy-phenyl)-phenyl-methanone and 4-ethyl-3-oxo-hexanenitrile (prepared as described in example 101 step A). Colorless oil. MS (ESI): 331.4 (M+H)+.
Sources & evidence
- ORD record
- ord-37cb911064a440d8b2a34fb7e8ece66c
- Source dataset
- uspto-grants-2015_12
- Patent number
- US09199938B2
Reaction notes
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