(2-Amino-4-methoxyphenyl)(phenyl)methanone → HCID 86683079, compound
Reaction equation
[NH2:1][C:2]1[CH:7]=[C:6]([O:8][CH3:9])[CH:5]=[CH:4][C:3]=1[C:10]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=O.[CH:18]1([C:23](=O)[CH2:24][C:25]#[N:26])[CH2:22][CH2:21][CH2:20][CH2:19]1>>[CH:18]1([C:23]2[C:24]([C:25]#[N:26])=[C:10]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)[C:3]3[C:2](=[CH:7][C:6]([O:8][CH3:9])=[CH:5][CH:4]=3)[N:1]=2)[CH2:22][CH2:21][CH2:20][CH2:19]1Participants
3
Procedure
The title compound was prepared in analogy to example 101 step B from (2-amino-4-methoxy-phenyl)-phenyl-methanone (prepared as described in example 121 step A) and 3-cyclopentyl-3-oxo-propionitrile (prepared as described in example 105 step A). White solid. MS (ESI): 329.4 (M+H)+.
Sources & evidence
- ORD record
- ord-162fa9d37697429e8cb230e784331232
- Source dataset
- uspto-grants-2015_12
- Patent number
- US09199938B2
Reaction notes
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