2-Pyrrolidone → HCID 86683083, compound

HRID 1497267Notes

Reaction equation

HRID 1497267 reaction equation
Cl[C:2]1[C:11]([C:12]#[N:13])=[C:10]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:20])[CH:8]=2)[N:3]=1.[NH:21]1[CH2:25][CH2:24][CH2:23][C:22]1=[O:26]>>[Cl:20][C:7]1[CH:8]=[C:9]2[C:4](=[CH:5][CH:6]=1)[N:3]=[C:2]([N:21]1[CH2:25][CH2:24][CH2:23][C:22]1=[O:26])[C:11]([C:12]#[N:13])=[C:10]2[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

Participants

3

Reactant 2

HCID 120252-PyrrolidoneHCID 86682946HCID 86682946, compound

Product 1

HCID 86683083HCID 86683083, compound

Procedure

The title compound was prepared in analogy to example 120 step A from 2,6-dichloro-4-phenyl-quinoline-3-carbonitrile (prepared as described in example 27 step B) and pyrrolidin-2-one. Yellow solid. MS (ESI): 348.4 (M+H)+.

Sources & evidence

ORD record
ord-9fc0a488134144a5b2591a206f752444
Source dataset
uspto-grants-2015_12
Patent number
US09199938B2

Reaction notes

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