HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromoethyl methyl ether → (rac)-(3aSR,6aRS)-3-(2-Methoxy-ethyl)-2-oxo-hexahydro-cyclopentaimidazole-1-carboxylic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromoethyl methyl ether | HCID 80972 | — |
| Reactant | (3aSR, 6aRS)-2-oxo-hexahydro-cyclopentaimidazole-1-carboxylic acid tert-butyl ester | HCID 67437675 | — |
| Product | (rac)-(3aSR,6aRS)-3-(2-Methoxy-ethyl)-2-oxo-hexahydro-cyclopentaimidazole-1-carboxylic acid tert-butyl ester | HCID 90039070 | — |
Reaction Steps
The title compound was prepared in accordance with the general method of example 1, step 2 starting from (rac)-(3aSR,6aRS)-2-oxo-hexahydro-cyclopentaimidazole-1-carboxylic acid tert-butyl ester (Example 1, step 1) and using 1-bromo-2-methoxyethane instead of iodoethane to yield the desired product as a light yellow oil which was directly used in the next step without further characterisation.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09199971B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-c9776199a6e540128d96745b0853ba97 |
| Source note | uspto-grants-2015_12 |