Methanol → HCID 117798896, compound

Participants

Reaction Steps

To a solution of methyl 1-(2,3-dimethyl-2H-indazol-5-yl)-2-oxo-1,2-dihydropyridine-4-carboxylate (450 mg) in dichloromethane (40 ml) was added diisobutylaluminum hydride (1 M toluene solution, 7.5 ml) at −78° C., and the mixture was stirred at the same temperature for 2 hr. To the reaction mixture were added methanol and water at the same temperature, and the mixture was filtered through celite, and concentrated under reduced pressure. The obtained residue was purified by silica gel column chromatography (dichloromethane/methanol) to give the title compound (220 mg).

Provenance & Evidence