tert-butyl N-[(benzyloxy)carbonyl]-4-(tert-butoxycarbonyl)-L-phenylalaninate → HCID 90281946, compound

Participants

Reaction Steps

To a solution of tert-butyl N-[(benzyloxy)carbonyl]-4-(tert-butoxycarbonyl)-L-phenylalaninate (570 mg) in ethanol (3.00 mL) and tetrahydrofuran (3.00 mL) was added 10% palladium-carbon (138 mg) under an argon atmosphere, and then followed by stirring at room temperature overnight under a hydrogen atmosphere. The reaction suspension was filtered through Celite, and the filtrate was concentrated under reduced pressure to obtain tert-butyl 4-(tert-butoxycarbonyl)-L-phenylalaninate (431 mg).

Provenance & Evidence