HCID 69671287, compound → HCID 69671286, compound

Participants

Reaction Steps

A solution of 6-(3-amino-4-methoxyphenyl)-3-(4-chloro-2-methoxyphenyl)-[1,2,4]triazolo[4,3-a]pyridine (50 mg, 0.131 mmol) in HCl/ethyl acetate (2M, 20 mL) was stirred at room temperature for 0.5 h. It was concentrated under reduced pressure to give the title compound (56 mg, 94% yield) as gray solids. 1H NMR (DMSO-d6): 8.32 (s, 1H), 8.10 (d, J=9.6 Hz, 1H), 7.95 (dd, J=9.6 and 1.5 Hz, 1H), 7.79 (d, J=2.1 Hz, 1H), 7.73 (dd, J=8.7 and 2.1 Hz, 1H), 7.66 (d, J=8.1 Hz, 1H), 7.45 (d, J=1.5 Hz, 1H), 7.32-7.27 (m, 2H), 3.94 (s, 3H), 3.93 (s, 3H). MS: m/z 381.2 [M+H+].

Provenance & Evidence