HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzyl-3-methyl-5-nitroindazole → 1-Benzyl-3-methyl-1H-indazol-5-ylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzyl-3-methyl-5-nitroindazole | HCID 21952162 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Platinum | HCID 23939 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 1-Benzyl-3-methyl-1H-indazol-5-ylamine | HCID 54103309 | — |
Reaction Steps
1-Benzyl-3-methyl-5-nitroindazole (0.15 g) in THF (15 ml) was treated with platinum on carbon (0.05 g, 5%) under an atmosphere of hydrogen at room temperature. When hydrogen uptake was complete, the mixture was filtered and concentrated in vacuo to give the title compound; m/z (M+1)+ 268.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09199973B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-c1dd49f0521e4ed69d80adc1371b69e0 |
| Source note | uspto-grants-2015_12 |