HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,6-Dichloropyrido[3,4-d]pyrimidine → (6-Chloropyrido[3,4-d]pyrimidin-4-yl)-(4-(3-fluorobenzyloxy)-phenyl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,6-Dichloropyrido[3,4-d]pyrimidine | HCID 10821876 | — |
| Reactant | 4-(3-Fluoro-benzyloxy)-phenylamine | HCID 16775314 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | (6-Chloropyrido[3,4-d]pyrimidin-4-yl)-(4-(3-fluorobenzyloxy)-phenyl)-amine | HCID 21952062 | — |
Reaction Steps
4,6-Dichloro-pyrido[3,4-d]pyrimidine (1 g) and 4-(3-fluorobenzyloxy)aniline (1.08 g) in acetonitrile (70 ml) were reacted together as in Procedure A. The product was collected by filtration as a yellow solid (1.86 g); m/z 381 (M+1)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09199973B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-002269f329484c1880a4f27ca57623dc |
| Source note | uspto-grants-2015_12 |