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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1497625Generated: October 30, 2026

4-(Phenylsulfonyl)aniline → 6-Chloro-4-(4-phenylsulphonylanilino)pyrido[3,4-d]pyrimidine

https://huagongshe.com/reaction/1497625

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Phenylsulfonyl)anilineHCID 516666—
Reactant4,6-Dichloropyrido[3,4-d]pyrimidineHCID 10821876—
Product6-Chloro-4-(4-phenylsulphonylanilino)pyrido[3,4-d]pyrimidineHCID 21952165—

Reaction Steps

Prepared according to Procedure A from 4-benzenesulphonylaniline (Helv. Chim. Acta., 1983, 66 (4), 1046) and 4,6-dichloropyrido[3,4-d]pyrimidine; [2H6]-DMSO 9.09 (1H, s), 8.80-8.88 (2H, m), 8.19 (2H, d), 7.94-8.09 (4H, m), 7.53-7.20 (3H, m); m/z (M+1)+ 397.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09199973B2
Source datasetuspto-grants-2015_12
ORD IDord-57898411504a4a198c8031bf92c05a5b
Source noteuspto-grants-2015_12